Businesses for Sale in Port St. Lucie, FL

A recently constructed self-storage facility on Florida's Treasure Coast with 216 climate-controlled drive-up units and exceptional highway visibility with over 32,000 vehicles passing daily. The dense surrounding population and notably low existing square-footage per capita in the immediate trade area support a strong lease-up trajectory. Hurricane-rated construction and proximity to major national retailers reinforce the facility's competitive positioning in a high-growth coastal Florida market.

This second-generation restaurant space in Port St. Lucie, Florida comes fully built out with a beer and wine license already in place, significantly reducing the time and cost a new operator would incur starting from scratch. The existing buildout supports immediate operations, allowing a buyer to focus on concept execution rather than construction. The Treasure Coast market offers growing residential density and steady tourist traffic that supports consistent restaurant demand.

Situated in the Port St. Lucie, Florida region, this upscale Italian restaurant has earned regional recognition for its fresh seasonal menu and curated wine program, drawing diners from a broad geographic catchment. Consistently high ratings and strong word-of-mouth underpin a loyal customer base spanning both locals and destination visitors. The business generates solid owner earnings at a purchase price that implies an attractive multiple relative to its established reputation.

Established Income-producing entertainment & recreation business serving the Port St. Lucie metro. The business generates meaningful owner earnings, supporting an acquisition in the $5M–$10M range. Exact location, full description, and seller details are available after sign-up.

This commercial-focused gutter and soffit installation contractor in the Port St. Lucie, Florida area operates with state-of-the-art cutting equipment that enables fabrication of multiple specialized gutter profiles, including uncommon large-format commercial systems. Revenue and profits have grown consistently for four consecutive years, reflecting both strong regional demand and the company's differentiated equipment capabilities. Expansion into adjacent residential markets or nearby counties represents a clear and immediate growth pathway for a new owner.

A full-service hospitality and events operation on Florida's Treasure Coast generating revenue across weddings, corporate events, banquets, room rentals, and food and beverage service. The business owns its real estate and benefits from a distinctive event setting that drives repeat bookings and group business. Multiple diversified revenue streams reduce seasonal risk and provide a buyer with multiple levers for growth.

This multi-location independent diagnostic testing facility specializes in the diagnosis and management of obstructive sleep apnea, offering both in-lab and home sleep testing across two fully equipped clinical sites in the Port St. Lucie area. The practice holds accreditation from a leading sleep medicine body and benefits from a diversified payer mix weighted toward commercial and government reimbursement, providing revenue stability. The combination of clinical credibility, established referral relationships, and essential-service positioning makes this an attractive platform for a healthcare operator or physician looking to enter the sleep medicine market.

This turnkey waterfront restaurant in the Port St. Lucie area generates approximately $2.5 million in annual revenue and benefits from direct dock access, allowing boat-in patronage that creates a premium customer experience unavailable to most competitors. The underlying waterfront real estate is included in the offering and is independently valued at $3.8 million, making this a combined business and real estate acquisition in a high-traffic tourism corridor. The infrastructure, staffing, and operational layout are fully in place to support immediate continuity under new ownership.

This upscale restaurant in affluent Martin County, Florida generates over $2.7 million in annual sales under a long-term lease secured through 2040 with minimal annual rent escalation, providing exceptional economics for a food and beverage operator. The property features both indoor dining and a unique covered outdoor dining area with dual bars, a rare amenity in the Florida market. The combination of a below-market lease, high-volume sales, and a distinctive physical footprint creates a durable competitive advantage for a new owner.